Smooth Away Frown Lines with Confidence
What Is Letybo®?
Letybo is an FDA-approved neuromodulator used to temporarily improve the appearance of moderate to severe frown lines (glabellar lines) between the eyebrows.
Trusted globally and backed by extensive clinical research, Letybo offers an effective option for patients seeking smoother skin while maintaining natural facial expression.
At Renove Medical Spa, Dr. Michelle Parsons carefully customizes Letybo treatments to deliver balanced, refreshed results — never stiff or overdone.
How Letybo Works
Frown lines form when the muscles between the eyebrows repeatedly contract during facial expressions such as concentrating or frowning.
Letybo works by temporarily relaxing these muscles, reducing their activity and allowing the skin to appear smoother and more relaxed. Results typically begin to appear within a few days and continue to improve over the first one to two weeks.
What Letybo Treats
Letybo is FDA-approved for:
-
Frown lines between the eyebrows (glabellar lines)
Like other neuromodulators, treatment may be tailored based on individual anatomy and aesthetic goals.
What Results Can You Expect?
Clinical studies have shown Letybo to be:
-
Effective in softening moderate to severe frown lines
-
Fast-acting, with some patients noticing improvement as early as Day 1
-
Long-lasting, with results typically lasting up to 3–4 months
Patients report natural-looking results with preserved facial movement.
Safety & Clinical Experience
Letybo has been evaluated in extensive clinical studies involving more than 1,200 patients across multiple study centers worldwide. The most commonly reported side effect was headache, occurring in a small percentage of patients.
As with all neuromodulators, side effects are generally mild and temporary when administered by an experienced medical professional.
What to Expect from Treatment
-
Quick in-office treatment (about 10–15 minutes)
-
Minimal discomfort
-
No downtime
-
Return to daily activities immediately
Your medical history and treatment goals will be reviewed thoroughly prior to treatment.
Letybo vs. Other Neuromodulators
Letybo is one of several neuromodulators offered at Renove Medical Spa. While all neuromodulators work similarly, subtle differences in formulation and individual response may make one option better suited for certain patients.
During your consultation, Dr. Michelle Parsons at Renove Medical Spa will help determine whether Letybo, Botox, Jeuveau, Xeomin, Dysport, or Daxxify is the best choice for your needs.
Is Letybo Right for You?
Letybo may be a great option if you:
-
Want to soften frown lines
-
Prefer a precise, well-studied neuromodulator
-
Want natural results without a frozen appearance
A consultation with Dr. Michelle Parsons at Renove Medical Spa will determine if Letybo is right for you.





